British company launches multi-layer immune support formula

29 June 2020 - The last three months has seen an unprecedented surge in demand for products which support immune health with sales of vitamins and supplements soaring 19.5% in a four-week period alone [1]. British all-natural nutraceutical brand, Works With Water, predicts this trend will not only intensify, but is here to stay, as Brits emerge from lockdown and start to resume ‘normal’ life outside their homes.

In response, the company, in partnership with leading ingredients specialists, Nutraceuticals Group Europe, has brought forward the release of a UK first nutritional supplement. PRAVIRAL immune support® contains a blend of seven rigorously-researched immune protection ingredients, which Works With Water has labelled the ‘Super Seven’.

PRAVIRAL immune support

Providing a powerful multi-layer immune effect, PRAVIRAL immune support’s Super Seven includes Yeast Beta Glucan (1,3 /1,6) - a natural immune support with almost 1,000 clinical studies suggesting this ingredient can both prime and support the immune system in multiple ways, including the body’s first line of defence against viral and bacterial infection; Colostrum – rich in macronutrients, proteins and antibodies which kick start immune function in newborns and can provide a much needed boost to immune health throughout life; Oligofructose - a prebiotic fibre which aids gut health; while Vitamins A (Retinol), D3, B9 (Folic Acid) and Zinc are proven to support the body’s response to infection.

No other product on the market combines optimum doses of the Super Seven in one formulation. The efficacy of each of the seven ingredients - naturally sourced using the highest grades available - is backed up by extensive scientific evidence.[1]

“The immune system is central to health and wellbeing as it affects every part of your body. The stronger your immune system, the better your body can combat bacterial, viral and fungal infections. Maintaining a healthy immune system has never been more important,” says Jules Birch, Works With Water Nutraceuticals founder and managing director.

“While a balanced diet rich in vitamins is essential, supplements have a role to play in helping to boost immune defences. Sometimes though, knowing what, and how much to take can be overwhelming, particularly at the moment when there is a lot of attention around this subject and ingredient quality and concentration varies significantly between products.

“Our formulation is developed with this in mind; it’s simply a sachet containing a delicate balance of seven superstar immune health ingredients mixed into a hot or cold drink once a day,” said Jules.

A 14-day pack of PRAVIRAL immune support® retails for £13.99 and is suitable for vegetarians and diabetics. Visit workswithwater.com for more information.

[1] The Grocer, 22 May 2020, Immunity to your door: healthcare and supplements category report 2020

Ends…

For further information, to arrange an interview with Jules Birch or to request product samples, please contact Jules personally:
E: jules@workswithwater.com
M: 07748344220

Seven super ingredients, and nothing else.
Colostrum	Rich in immune boosting macronutrients, lactoferrin and antibodies
1-3 / 1-6 Beta Glucan	Reduces inflammation and primes and supports the immune system
Oligofructose	Prebiotic fibre from chicory root, improves mineral absorption in the gut, aiding digestive health
Vitamin A	Involved in the development of the immune system and regulating cellular immune response
Zinc Bisglycinate	Activates cells to fight pathogens and helps break down proteins in bacteria and viruses to slow infection
Vitamin D	Critical in activating immune defences, Vitamin D deficiency affects many people
Folic Acid (vitamin B9)	Helps to maintain immune function with potential to improve immune health in the elderly

The global nutraceuticals market is estimated to reach $722+ billion (USD) in the next seven years.

Notes to editors:

About Works With Water Nutraceuticals Limited (workswithwater.com)
PRAVIRAL immune support® is developed, manufactured, marketed and sold by Works With Water Nutraceuticals Limited – a UK based business founded in 2006 by Jules Birch.

The company formulates with functional ingredients that have solid, human-trialed science to support specific health claims for skin health and immune support.

Works With Water has a development and market expansion partnership with global ingredients specialists Nutraceuticals Group Europe. This global expertise and presence enables the development of highly effective nutritional products that are approved for use throughout Europe, US and Asia.

About Nutraceuticals Group Europe Ltd (https://nutraceuticalsgroup.com/uk)
Nutraceutical Group Europe is the UK’s leading specialist in bringing active natural health ingredients to the UK market. Specialists within the technical, regulatory and quality aspects of new product development, they play a key role in helping its customers and partners develop new premium markets.

Clinical Research, Reviews and Studies Referenced In Product Development:

*Ingredient*	Link to paper
Colostrum	Bovine colostrum as a biologic in clinical medicine: A review – Part II: Clinical studies International journal of clinical pharmacology and therapeutics · June 2008 https://drive.google.com/open?id=1AuLvsy7wiwRgSyGRifYSQihywoRP21ut Clinical applications of bovine colostrum therapy: a systematic review Nutrition Reviews® Vol. 72(4):237–254 https://drive.google.com/open?id=1kGcSZD8XblAQp8MqbI9DtbUxOhnQTiDt Bovine colostrum modulates immune activation cascades in human peripheral blood mononuclear cells in vitro The New Microbiologica: official journal of the Italian Society for Medical Virology (SIVIM) · April 2010 https://drive.google.com/open?id=14apgZPOzMAH26O1MYfJiPu8vQDURcdcS Effect of Bovine Colostrum Supplementation on Respiratory Tract Mucosal Defenses in Swimmers International journal of sport nutrition and exercise metabolism · June 2010 https://drive.google.com/open?id=1USV8iFw8Rf5PGm3qVb0MoJYpZN_2KVfd Effects of bovine colostrum supplementation on immune variables in highly trained cyclists J Appl Physiol 102: 1113–1122, 2007. https://drive.google.com/file/d/1NB0_CyM-C_7g8_lFaZb-XVaTbXTK2R40/view?usp=sharing Human colostrum oligosaccharides modulate major immunologic pathways of immature human intestine Nature: Volume 7, Number 6 - November 2014 https://drive.google.com/open?id=1FQKToiU4ohrCm3wlMED9JwUMOEPqomiR IGF-I, IgA, and IgG responses to bovine colostrum supplementation during training J Appl Physiol 93: 732–739, 2002. https://drive.google.com/open?id=1LoLbx7cN8-zaPROXALGZaJaaiLkmpAtu Modulation of human humoral immune response through orally administered bovine colostrum FEMS Immunology and Medical Microbiology 31 (2001) 93-96 https://drive.google.com/open?id=1oVm8drqdJHul3ajVENHHefcXbAyxdg5v The isolation and properties of the immune proteins of bovine milk and colostrum and their role in immunity: a review EMIL L. SMITH - University of Utah School of Medicine, Salt Lake City https://drive.google.com/open?id=1K39lEM-rsZyArGX2seDShOlBURTBBEK_
Beta Glucan	Dietary modulation of immune function by β-glucans Physiology & Behavior 94 (2008) 276–284 https://drive.google.com/open?id=1LYfB-nHanU4T7oScf6p7jc968GWIXMQf Anthrax-Protective Effects of Yeast Beta 1,3 Glucans Medscape General Medicine 5(1), 2003 https://drive.google.com/open?id=1UBnnGmWBTcYorXEc_5Ufi4blT-ANhRsC Baker’s yeast b-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk? British Journal of Nutrition (2013), 109, 478–486 https://drive.google.com/open?id=1-5F_AU2cvkt2GcfJnShioVHO-hNaWAsA Baker's Yeast Beta-Glucan Supplement Reduces Upper Respiratory Symptoms and Improves Mood State in Stressed Women Journal of the American College of Nutrition, 31:4, 295-300 https://drive.google.com/open?id=1NQhl9Ufqdb7vHW74WtjenHunzWelQo2P Clinical trials of yeast-derived β-(1,3) glucan in children: effects on innate immunity doi: 10.3978/j.issn.2305-5839.2014.02.01 - Feb 08 https://drive.google.com/open?id=1y8oR4wdbpbjewb9HYtBfvJidVaycuAJF Immune modulation by non-digestible and nonabsorbable beta-1,3/1,6-glucan Microbial Ecology in Health and Disease, 26:1, 27824 - May 2015 https://drive.google.com/open?id=1abhq5CMZxkryezc3rLx2Yh23HuBKdV-5 Immune-modulatory effects of Yeast Beta-1,3 / 1,6 D-glucan Stier et al. Nutrition Journal 2014, 13:38 https://drive.google.com/open?id=1fVK3-RVVspQosnjMA_hGtttgNBumsdSl A Double-Blind, Randomized, Placebo-Controlled Nutritional Study Using an Insoluble Yeast Beta-Glucan to Improve the Immune Defense System Food and Nutrition Sciences, 2012 https://drive.google.com/open?id=1-6opNuAv0Djomd8hQt2VChNe0r7by7XH Purification of Soluble Beta-Glucan with Immune-enhancing Activity from the Cell Wall of Yeast Biosci. Biotechnol. Biochem., 65 (4) - November 2000 https://drive.google.com/open?id=1mgnHsjL58ZZFrvYGcB1p0ViHaGc_zVJo
Oligofructose	Innate and adaptive immune effects of chicory root dietary fibers University of Groningen - 2015 https://drive.google.com/open?id=1QgeJKviw_Z7wW8KeUHhqR7LFqapPFROV Interactions between Dietary Chicory, Gut Microbiota and Immune Responses Swedish University of Agricultural Sciences Uppsala - 2013 https://drive.google.com/open?id=1uByE78_kI6VcDl13LXbTOMqIj3syhBAU Inulin and Oligofructose in Chronic Inflammatory Bowel Disease J. Nutr. 137: 2572S–2575S, 2007 https://drive.google.com/open?id=1PRdBNLBc9zPtz4bEHc71aoVzMi6dJYvT Inulin, oligofructose and immunomodulation British Journal of Nutrition (2005), 93, Suppl. 1, S49–S55 https://drive.google.com/open?id=1pFZnTaJXxVU44PPCWNhUawyH4QwW7Wjn Inulin, Oligofructose and Intestinal Function J. Nutr. 129: 1431S–1433S, 1999 https://drive.google.com/open?id=1h1Z84UDete5XkairdCDFzJLQXD-t4oC9 Pediatric Applications of Inulin and Oligofructose J. Nutr. 137: 2585S–2589S, 2007 https://drive.google.com/open?id=1QtBFCvx7b0_5Lq4Gg361n--SzQtZLOz3 Prebiotic Inulin Enriched with Oligofructose in Combination with the Probiotics Lactobacillus rhamnosus and Bifidobacterium lactis Modulates Intestinal Immune Functions in Rats American Society for Nutritional Sciences. 2003 https://drive.google.com/open?id=1Oq8x7404elBnUd18cvzDJeqRPm29mAye Prebiotic dietary fibres and the immune system Agro Food Industry Hi Tech · May 2008 https://drive.google.com/open?id=1OZsaSI8MCehMSeimyG8gUObFRA0ki9Qt Significance of Inulin Fructans in the Human Diet Comprehensive Reviews in Food Science and Food Safety - Vol 14, 2015 https://drive.google.com/open?id=1pSDlKJLZOVpNGSwyvkI62FwMQUo2Q0nn The bifidogenic effect of inulin and oligofructose and its consequences for gut health European Journal of Clinical Nutrition (2009) 63, 1277–1289 https://drive.google.com/open?id=1LSjpTlmpmEt88apvaOJp2txpLcYD6ykj
Vitamin A (Retinol)	Potentiation of Mitogen-induced Human T-Lymphocyte Activation by Retinolic Acid CANCER RESEARCH 45, 4128-4131, September 1985] https://drive.google.com/open?id=1lIdePRb9gIXu7ChxF1zLzCam2LzAfCYl The Role of Vitamin A and Related Retinoids in Immune Function Nutrition Reviews, Vol. 56, No. 1 https://drive.google.com/open?id=1xVhDeMH8VIu1IHOHIKAhM3eUSCvED4of Vitamin A Levels and Immunity in Humans Clinical And Diagnostic Laboratory Immunology, May 2002 https://drive.google.com/open?id=10_bLfyK8vduzFRSZFZFklohacdju10tP
Zinc Bisglycinate	Immune-Enhancing Role of Vitamin C and Zinc and Effect on Clinical Conditions Ann Nutr Metab 2006;50:85–94 https://drive.google.com/open?id=1yD2UQPDAf9Ppm3vzyqkoJEsy6g6vbClJ Zinc: dietary intake and impact of supplementation on immune function in elderly AGE (2013) 35:839–860 https://drive.google.com/open?id=14LF1cIcpet6qlctk3ERJspFsAf7LN1j1 Zinc in Human Health: Effect of Zinc on Immune Cells Wayne State University School of Medicine, 2008 https://drive.google.com/open?id=1Wv3U7ho1dQwIUJ-OlxncRfoJWznudhbu
Vitamin D	The vitamin D–antimicrobial peptide pathway and its role in protection against infection Future Microbiol. 2009 November ; 4: 1151. https://drive.google.com/open?id=1aivuy4qxDKpxz1QOgd29_rGc2rVNjLjz Vitamin D and inflammatory diseases Journal of Inflammation Research - May 2014 https://drive.google.com/open?id=1_jfTMyLfJ3OnzG6zRtiXubSBAKZh5cKT Vitamin D and Influenza Adv. Nutr. 3: 517–525, 2012 https://drive.google.com/open?id=1y9hHyEvcKhrhpSe9A8JfeNkfHHUspR4w Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity J Mol Med (Berl). 2010 May ; 88(5): 441–450 https://drive.google.com/open?id=1GnsN0Xink5K6M3gCKBhetg81J8fKfxTV Vitamin D and mucosal immune function Curr Opin Gastroenterol. 2010 November https://drive.google.com/open?id=114beO_hxq09xYKPKDGduSiJQUmaNz_sF Vitamin D and the antiviral state J Clin Virol. 2011 March https://drive.google.com/open?id=18kOqNVQ3bpk2_DvSZqVb2lfUAduoLs0n Vitamin D and the Immune System J Investig Med. 2011 August https://drive.google.com/open?id=1SwuULpgKBFV8CUUcka_-XIcWMihLHb5C The role of vitamin D3 & vitamin B9 (Folic acid) in immune system International Journal of Epidemiologic Research, 2016; 3(1): 69-85 https://drive.google.com/open?id=1ncNoy4L5dnQ_92nKYPLEO7cU_aEPVvM9
Vitamin B9 (Folic Acid)	Folic Acid Supplementation and Pregnancy: More Than Just Neural Tube Defect Prevention Rev Obstet Gynecol. 2011 https://drive.google.com/open?id=1Quzjd2zOwy8Cte674cx5i8FeRNAgL2sj Nutritional components regulate the gut immune system and its association with intestinal immune disease development Journal of Gastroenterology and Hepatology 2013 https://drive.google.com/open?id=1C-adixd2_oPX5AjMEDREV0dHOmU2Yd93 Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses British Journal of Nutrition (2007), 98, Suppl. 1, S29–S35 https://drive.google.com/open?id=17FD5I3WLB6F3GmG1-VXRtDpKtTonTRGg The effects of vitamin B on the immune/cytokine network and their involvement in depression Maturitas 96 (2017) 58–71 https://drive.google.com/open?id=195n8CTuIyuYzXPye_4kxnOcCF_lYkqB7 The role of vitamin D3 & vitamin B9 (Folic acid) in immune system International Journal of Epidemiologic Research, 2016; 3(1): 69-85 https://drive.google.com/open?id=1ncNoy4L5dnQ_92nKYPLEO7cU_aEPVvM9 Vitamin-mediated regulation of intestinal immunity Frontiers in Immunology, July 2013 https://drive.google.com/open?id=1fmoswWeYPLwKu_wHPYjsBVSTiBa_4C7u